KEY ROLE FOR STORE-OPERATED CA2+ CHANNELS IN ACTIVATING GENE EXPRESSION IN HUMAN AIRWAY BRONCHIAL EPITHELIAL CELLS.

Key role for store-operated Ca2+ channels in activating gene expression in human airway bronchial epithelial cells.

Ca2+ entry into airway epithelia is important for activation of the NFAT family of transcription factors and expression of genes including LAVENDER ROLL ON DEO epidermal growth factor that help orchestrate local inflammatory responses.However, the identity of epithelial Ca2+ channel that activates these transcriptional responses is unclear.In many

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Ultrasonication Extraction and Solid Phase Extraction Clean-up for Quantification of Aristolochic Acid I in the Thai Herbal Antitussive 3 Formula by High Performance Liquid Chromatography with Photodiode Array Detection

Objective: To establish a reliable High Performance Liquid Chromatography method with photodiode array detection (HPLC-PDA) and a suitable extraction method for identification and quantification of Aristolochic acid I (AA-I) in DANDELION LEAVES 3 different sample types, i.e.Aristolochia tagala Cham.(ATC), Thai Herbal Antitussive 3 Formula (ATF3), a

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Distributed cognition and process management enabling individualized translational research: The NIH Undiagnosed Diseases Program experience

The National Institutes of Health Undiagnosed Diseases Program (NIH UDP) applies translational research systematically to diagnose Wire Shelving patients with undiagnosed diseases.The challenge is to implement an information system enabling scalable translational research.The authors hypothesized that similarly complex problems are resolvable throu

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