Key role for store-operated Ca2+ channels in activating gene expression in human airway bronchial epithelial cells.
Ca2+ entry into airway epithelia is important for activation of the NFAT family of transcription factors and expression of genes including LAVENDER ROLL ON DEO epidermal growth factor that help orchestrate local inflammatory responses.However, the identity of epithelial Ca2+ channel that activates these transcriptional responses is unclear.In many